transformation_schedule = client.transformations.schedules.retrieve(id=1)
transformation_schedule.is_paused = True
res = client.transformations.schedules.update(transformation_schedule)

from cognite.client.data_classes import TransformationScheduleUpdate
my_update = TransformationScheduleUpdate(id=1).interval.set("0 * * * *").is_paused.set(False)
res = client.transformations.schedules.update(my_update)

{
  "items": [
    {
      "id": 123,
      "externalId": "<string>",
      "createdTime": 123,
      "lastUpdatedTime": 123,
      "interval": "0 0 * * *",
      "isPaused": true
    }
  ]
}